Collagen biostimulators

HArmonyCa

Collagen biostimulators – skin structure

Support with hyaluronic acid and collagen biostimulation with calcium hydroxyapatite (CaHA)

HArmonyCa is a hybrid injectable treatment that combines hyaluronic acid (HA) with calcium hydroxyapatite (CaHA) microspheres, bringing together two complementary mechanisms in a single product.

Hyaluronic acid provides immediate tissue support, while calcium hydroxyapatite progressively stimulates collagen production, contributing over time to improved firmness and skin structure.

HArmonyCa may be considered when the aim is to support the tissues and improve facial contour and skin firmness, combining the immediate effect of hyaluronic acid with progressive biostimulation.

The treatment is used in particular in the lateral and middle regions of the face and along the jawline, the exact areas being established according to the anatomy and needs of each patient.

HArmonyCa is not intended for all areas of the face, which is why the selection of the area and adherence to the correct injection plan are essential.

The procedure

The treatment begins with an individual medical assessment, during which facial anatomy, the degree of laxity, the distribution of volumes and tissue quality are analyzed.

The product is administered in carefully established anatomical planes. The quantity, the areas treated and the injection technique are established individually by the doctor.

Results

The hyaluronic acid component provides a supporting effect that is visible after the treatment, while the effect associated with collagen stimulation develops progressively over the following months.

The evolution and duration of the result differ according to individual particularities and the area treated.

Contraindications and precautions

The treatment is not performed during pregnancy or breastfeeding, in the presence of an active infection or inflammation in the treated area, or in cases of known hypersensitivity to the components of the product.

The presence of an autoimmune disease, in particular a systemic connective tissue disease, as well as immunosuppressive treatments, require a careful individual medical assessment before the procedure.

Before the treatment, medical history, medication taken and previous injectable procedures are assessed.

The treatment is performed exclusively after a consultation and medical assessment. The indication, quantity, areas treated and injection technique are established individually by the doctor.

Medical content written and reviewed by Dr. Mihaela Marinescu — Specialist in Geriatrics and Gerontology · Medical Director, Maison Longévité. Last reviewed: 7 October 2026. Meet the medical team
This page is for information and education. It does not replace a medical consultation or the individual recommendations of a healthcare professional.

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